Coronary Trials
- OASIS 9
A multicenter, international SYNERGY Stent registry that is embedded within a randomized, blinded, double-dummy, 2×2 factorial design trial of colchicine versus placebo and spironolactone versus placebo in patients with ST-elevation myocardial infarction who have undergone primary percutaneous coronary intervention (PCI).
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT03048825
- LIBerate-H2H
More information coming soon.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
Peripheral Trials
- CREST II
Carotid revascularization and medical management for asymptomatic carotid stenosis trial
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT02089217
- DELIVER
early feasibility study to evaluate the safety and performance of intravascular hepatic denervation using the Metavention Integrated Radio Frequency Denervation System (iRF System) to improve glycemic control in type 2 diabetes subjects.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
www.clinicaltrials.gov/ct2/show/NCT04285554
- C-TRACT
The purpose of this study is to determine if the use of image-guided, endovascular therapy (EVT) is an effective strategy with which to reduce Post Thrombotic Syndrome (PTS) disease severity and improve quality of life in patients with established disabling iliac-obstructive post thrombotic syndrome (DIO-PTS).
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT03250247
- TARGET BP
A randomized, blinded, multi-center, international, sham-procedure controlled trial, comparing renal denervation performed with the Peregrine System Kit in the treatment group to the sham control group (without renal denervation – no alcohol infusion). Subjects will be randomized in a 1:1 fashion to treatment versus sham control via central randomization.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT02910414
- MiSET-1
Evaluate the utilization and clinical benefits of a home-based, mobile-delivered supervised exercise therapy program compared to usual care.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
- Elegance
The ELEGANCE Registry’s objective is to collect Real-World Data (RWD), including populations previously not represented in Peripheral Vascular Disease (PVD) trials, health economics data, and to support the safe use of commercially available Boston Scientific Corporation (BSC) drug-eluting devices for the treatment of lesions located in the peripheral vasculature.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT04674969?term=04674969&draw=2&rank=1
Structural Heart Trials
- EARLY TAVR
To establish the safety and effectiveness of the Edwards SAPIEN 3 (Edwards Lifesciences, Irvine, California) Transcatheter Heart Valve (THV) compared with clinical surveillance (CS) in asymptomatic patients with severe, calcific aortic stenosis
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT03042104?term=early+tavr&draw=1&rank=1
- AMPLATZER™ PFO Occluder Post-Approval Study
AMPLATZER™ PFO Occluder Post Approval Clinical Study is a single arm, multi-center study to confirm the safety and effectiveness of the AMPLATZER™ PFO Occluder, in a post approval setting, in patients with a PFO who have had a cryptogenic stroke confirmed by a study neurologist.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT03309332
- ACURATE IDE
A prospective, multicenter trial designed to evaluate the safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for TAVR in subjects who have sever native aortic stenosis and are indicated for TAVR.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
Website pending…
- AltaValve EFS
Prospective, single-arm, multicenter study to evaluate the safety and performance of the AltaValve for the treatment of moderate to severe or severe mitral valve regurgitation in subjects who are considered high risk for mortality and morbidity from conventional open-heart surgery.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT03997305
- SUMMIT
Prospective, controlled, multicenter clinical investigation of the Tendyne Mitral Valve System for the treatment of eligible subjects with symptomatic, severe, mitral regurgitation.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
Website pending…
- PROTECTED TAVR
To demonstrate that use of the Sentinel® Cerebral Protection System significantly reduces the risk of peri-procedural stroke (≤72 hours) after transcatheter aortic valve replacement (TAVR).
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT04149535
- OPTIMIZE PRO
The purpose of this study is to collect clinical evidence on valve performance and procedural outcomes associated with an “optimized” TAVR care pathway and using the Evolut™ PRO and Evolut™ PRO+ device.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT04091048
- CHAMPION AF
This study is a prospective, randomized, multi-center global investigation. Subjects will be randomized to either the WATCHMAN FLX Left Atrial Appendage Closure Device (“Device Group”) or a commercially available non-vitamin K oral anticoagulant (“Control Group”).
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT04394546?term=champion+af&cntry=US&draw=2&rank=1
EP Trials
- ARTESIA
Prospective, randomized, parallel group, double-blind trial To determine if the use of apixaban in patients with SCAF will reduce the incidence of stroke and systemic embolism compared to aspirin.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT01938248?term=artesia&draw=1&rank=1
- SOLVE CRT
A prospective, multi-center, randomized, controlled, double blinded, pivotal trial to study the safety and efficacy of the WiSE-LV System for Cardiac Re-synchronization Therapy. The WiSE-LV System is an implantable cardiac pacing system capable of delivering pacing energy to the left ventricle of the heart without using a pacing lead.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/study/NCT02922036
- INTERRUPT AF
A prospective, non-randomized, multicenter (global), post approval clinical study (PAS) to evaluate open irrigated ablation catheters with high resolution mapping to treat paroxysmal atrial fibrillation.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT03729830
- aMAZE
A prospective, multicenter, randomized (2:1) controlled study to evaluate the safety and effectiveness of the LARIAT System to percutaneously isolate and ligate the Left Atrial Appendage from the left atrium as an adjunct to planned pulmonary vein isolation (PVI) catheter ablation in the treatment of subjects with symptomatic persistent or longstanding persistent atrial fibrillation.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT02513797
- EV-ICD
Designed to demonstrate safety and efficacy of the Extravascular Implantable Cardioverter Defibrillator (EV ICD) System.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT04060680
- ARCADIA
Description coming soon…
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
- OPTION
Description coming soon…
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
- iCLAS
Clinical study to evaluate the safety and efficacy of the Adagio AF Cryoablation System (iCLAS™) in the ablation treatment of symptomatic, persistent atrial fibrillation (PsAF).
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
- HEAL
The objective of this study is to gather information on participants returning at time of CIED change-out or revision who underwent a device implantation with either a CanGaroo® envelope, Tyrx™ envelope, or no envelope.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT04645173?cond=cangaroo&draw=2&rank=1
- Newton AF
Study to establish the safety and effectiveness of the IntellaNav StablePoint Catheter and Force-Sensing System in subjects with symptomatic, drug refractory, recurrent paroxysmal atrial fibrillation.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
Heart Failure Trials
- Rebalance HF
The objective of this clinical evaluation is to assess the safety and initial effectiveness of catheter-based unilateral ablation of the right greater splanchnic nerve (GSN) in subjects having heart failure with preserved ejection fraction (HFpEF).
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://clinicaltrials.gov/ct2/show/NCT04592445?cond=rebalance+hf&draw=2&rank=1
Registry
- THEME
A multicenter, prospective observation registry. By collecting prospective descriptive data, provide insight into disease defining characteristics resulting in the clinical decision to use TandemHeart for mechanical support and enhance knowledge of best practice regarding clinical management, weaning and removal/exit strategies.
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com
https://www.clinicaltrials.gov/ct2/show/NCT02326402
- Care HF
Cardiovascular and renal treatment in heart failure patients with Hyperkalemia or at high risk of hyperkalemia
If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com