Coronary Trials

 

  • EVOLVE SHORT DAPT

The EVOLVE Short DAPT Study is a prospective, multicenter, single-arm study designed to assess the safety of 3-month DAPT in subjects at high risk for bleeding undergoing PCI with a SYNERGY Stent System.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://www.clinicaltrials.gov/ct2/show/NCT02605447

 

  • ALLSTAR

Randomized, Double-Blind, Placebo-Controlled Phase I/II Study of the Safety and Efficacy of Intracoronary Delivery of Allogeneic Cardiosphere-Derived Cells in Patients With an Anterior Myocardial Infarction and Ischemic Left Ventricular Dysfunction (ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration, ALLSTAR)

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT01458405

 

  • ARTEMIS

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02406677

Peripheral Trials

 

  • CONFIDENCE

A prospective, multicenter, single-arm, open label clinical study to evaluate the safety and effectiveness of MicroVention, Inc. Roadsaver™ Carotid Stent System used in conjunction with the Nanoparasol® embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://www.clinicaltrials.gov/ct2/show/NCT02657707

 

  • TOBA II

Tack Optimized Balloon Angioplasty Study for the Superficial Femoral and Proximal Popliteal Arteries Using the Tack Endovascular System™

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02522884

 

  • LUTONIX BTK

A Prospective, Multicenter, Single Blind, Randomized, Controlled Trial Comparing the Lutonix Drug Coated Balloon vs. Standard Balloon Angioplasty for Treatment of Below-the-Knee (BTK) arteries

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT01870401

 

  • CREST II

Carotid revascularization and medical management for asymptomatic carotid stenosis trial

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02089217

 

  • SAFE DCB

A Prospective, Multicenter, Single Arm, Real-World Registry Assessing the Clinical Use of the Lutonix® 035 Drug Coated Balloon (DCB) Catheter in Arteries of the Superficial Femoral Artery (SFA) and Popliteal Artery (PA) (SAFE-DCB U.S. Registry)

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02424383

 

  • LEOPARD

Multicenter, Observational, Post-Market, Real World Study to Assess Outcomes of Patients Treated with the AFX System compared to other EVAR devices for Endovascular Abdominal Aortic Aneurysm Repair

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02407457

 

  • REDUCE HTN: REINFORCE Study

Renal Denervation Using the Vessix Reduce™ Catheter and Vessix™ Generator for the Treatment of HyperTensioN: REINFORCE

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02392351

 

  • MIMICS

Evaluation of Safety and Effectiveness of the BioMimics 3DTM Stent System in the Femoropopliteal Arteries of Patients with Symptomatic Peripheral Arterial Disease

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02400905

 

  • VOYAGER

An international, multicenter, randomized, double-blind, placebocontrolled phase 3 trial investigating the efficacy and safety of rivaroxaban to reduce the risk of major thrombotic vascular events in patients with symptomatic peripheral artery disease undergoing lower extremity revascularization procedures.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02400905

Structural Heart Trials

 

  • PARACHUTE

The study (experimental) procedure involves the implantation of a small membrane (called the Parachute Implant) into the left ventricle of your heart.  This study will test the safety and effectiveness of a new device for the treatment of heart failure. The device is an investigational device and is not approved for use by the U.S. Food and Drug Administration.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT01614652

 

  • REPRISE III

REpositionable Percutaneous Replacement of Stenotic Aortic Valve through Implantation of Lotus™ Valve System – Randomized Clinical Evaluation: To evaluate the safety and effectiveness of the Lotus™ Valve System for transcatheter aortic valve replacement (TAVR) in symptomatic subjects with calcific, severe native aortic stenosis who are considered at extreme or high risk for surgical valve replacement.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02202434

 

  • GALILEO

To assess whether a rivaroxaban-based anticoagulation strategy, following successful TAVR, compared to an antiplatelet-based strategy, is superior in reducing death or first thromboembolic events (DTE).  To assess whether a rivaroxaban-based strategy, following TAVR, compared to an antiplatelet-based strategy, is non-inferior towards primary bleeding events (PBE).

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://www.clinicaltrials.gov/ct2/show/NCT02556203

 

  • PARTNER 3

To establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve in patients with severe, symptomatic aortic stenosis who are at low operative risk for standard aortic valve replacement (AVR).  Prospective, randomized, controlled, multi-center trial. Patients having an operative mortality < 2% (low operative risk) for surgical aortic valve replacement will be randomized 1:1 to receive either transcatheter heart valve replacement (TAVR) with the Edwards SAPIEN 3 or aortic valve replacement with a commercially available surgical bioprosthetic valve. Patients will be seen for follow-up visits at discharge, 30 days, 6 months, and annually through 10 years.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://www.clinicaltrials.gov/ct2/show/NCT02675114

 

  • SALUS

The Safety and Effectiveness of the Direct Flow Medical Transcatheter Aortic Valve System in Patients at Extreme Surgical Risk with Severe Aortic Stenosis

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02163850

EP Trials

 

  • ADAPT RESPONSE

Medtronic, Inc. is sponsoring the AdaptResponse study; a prospective, randomized, controlled, interventional, single-blinded, multi-center, post-market, global Cardiac Resynchronization Therapy (CRT) in heart failure (HF) clinical study. The purpose of this clinical study is to test the hypothesis that market released CRT devices which contain the AdaptivCRT® (aCRT) algorithm have a superior outcome compared to standard CRT devices in CRT indicated patients with normal atrio-ventricular (AV) conduction and left bundle branch block (LBBB).

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02205359

 

  • ENABLE MRI

The objective of this study is to collect data to confirm the safety and effectiveness of the ImageReady™ MR Conditional Defibrillation System when used in the 1.5T MRI environment under the labeled Conditions of Use.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://www.clinicaltrials.gov/ct2/show/NCT02652481

 

  • WRAP IT

World-wide Randomized Antibiotic EnveloPe Infection PrevenTion Trial

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://clinicaltrials.gov/ct2/show/NCT02277990

 

  • MRI READY

A Clinical Evaluation of the Durata or Optisure High Voltage Leads and Ellipse VR ICD Undergoing MRI, an IDE Study (MRI Ready IDE).  To demonstrate safety and efficacy of the Durata or Optisure high voltage lead and Ellipse VR ICD in an MRI environment.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://www.clinicaltrials.gov/ct2/show/NCT02787291

 

  • SJM MRI Diagnostic Imagin Registry

This study is a prospective, non-randomized, multi-center study of subjects implanted with an SJM pacemakers, implantable cardioverter defibrillator (ICD), and cardiac resynchronization therapy (CRT) devices who are clinically indicated for a non-thoracic MRI scan.

 

If you would like additional information regarding this trial please visit the website below or contact researchopportunities@prairieresearch.com

https://www.clinicaltrials.gov/ct2/show/NCT02807948

Heart Failure Trials

 

  • CHAMP HF

Observational Registry of Treatment Patterns in the U.S. Heart Failure Patients with Reduced Ejection Fraction

 

If you would like additional information regarding this trial please contact researchopportunities@prairieresearch.com

More Coming soon…..